ABSTRACT
OBJECTIVE@#To explore the effect of septoplasty on the modality of inferior turbinate in patients with a deviated nasal septum.@*METHOD@#Twenty-three patients with nasal septum deviation underwent septoplasty without turbinate surgery. All patients underwent CT imaging scans before and 3 months after the surgery. The thicknesses of the medial mucosa, lateral mucosa,and the cross-sectional areas of the inferior turbinate were measured and compared using the Wilcoxon signed rank test. P0. 05), and the cross-sectional area of the inferior turbinate was(139. 8 +/- 35.6) mm2 to( 110. 3 +/- 22.6)mm2 (P0. 05), the thicknesses of the lateral mucosa of the inferior turbinate was(1. 9+/-1. 1) mm to (1. 9+/-1.3) mm (P>0. 05), and the cross-sectional area of the inferior turbinate was(104. 5+/-15. 8)mm2 to(108. 3 +/- 20. 8)mm2 (P>0. 05), pre- and post-operatively.@*CONCLUSION@#The compensatory hypertrophic inferior turbinate may be self-adaptability in modality soon after septoplasty, thus surgeons must take it into consideration before performing turbinate surgery.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Nasal Septum , General Surgery , Rhinoplasty , Tomography, X-Ray Computed , Turbinates , Diagnostic ImagingABSTRACT
OBJECTIVE@#To study cellular immune function of palatine tonsil B lymph cell.@*METHOD@#The phenotype of palatine tonsil cells (PTC) and that of peripheral blood mononuclear cell (PBMC) were compared using fluorescence staining and flow cytometry (FCM) analysis, then immunomagnetic beads were used to separate CD3- cell in PTC and PBMC. The proliferation function of CD3- lymph cell of PTC and PBMC was tested after stimulated by CD20mAb.@*RESULT@#FCM analysis founding that 71.2% PTC express CD20 with higher mean fluorescence intensity, MFI, compared to the 15.5% in PBMC. There's no significant difference between the proliferation of PTC and PBMC B lymph cell.@*CONCLUSION@#CD20 expression is different in PTC and PBMC, but corresponding function is still unknown.
Subject(s)
Adult , Humans , Antigens, CD20 , Metabolism , B-Lymphocytes , Cell Biology , Allergy and Immunology , Metabolism , Flow Cytometry , Palatine Tonsil , Cell Biology , Allergy and ImmunologyABSTRACT
Objective: To investigate the surgical methods and outcomes of the enlarged translabyrinthine approach in the removal of large acoustic neuromas. Methods: A large mastoidectomy involved complete exposure of the sigmoid sinus, the dura behind the sinus for at least 1 cm, the superior petrosal sinus and the middle fossa dura. The jugular bulb was exposed and pressed downwards if necessary. The internal auditory meatus was skeletonized and uncovered for at least 270°.The debulking of the tumor began inside the anterior and inferior poles in order to find the brainstem and the facial nerve root as early as possible, and then the dissection of the nerve was done medially to laterally. Intraoperative facial nerve monitoring and postoperative CT and MRI were done in all cases. Results: Total removal was achieved in all 18 patients with tumors larger than 3 cm (mean size: 4.2 cm). There were no deaths or other complications such as intracranial infection and persistent cerebrospinal fluid leakage. There were no obvious cerebral sequelae. The facial nerve was preserved both anatomically and functionally in 14 cases, with Grade Ⅰ or Ⅱ in 8 cases, Grade Ⅲ or Ⅳ in 6 cases. Nerve interruption occurred in 4 patients who all had severe facial palsy or nerve interruption before operation. Sixteen patients resumed work within 1-3 months. Conclusion: Total removal of large acoustic neuroma could be acomplished via the translabyrinthine approach, with good preservation of facial nerve function and minimum incidence of morbidity.